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June 24, 2011

Q&A About Marijuana 2

Continued Q&A about Marijuana Use provided by the National Institute on Drug Abuse and National Institutes on Health.

Q: How does marijuana affect the brain?
A: THC affects the nerve cells in the part of the brain where memories are formed. This makes it hard for the user to recall recent events (such as what happened a few minutes ago). It is hard to lean while high-a working short-term memory is required for learning and performing tasks that call for more than one or two steps. Among a group of long-time heavy marijuana users in Costa Rica, researchers found that the people had great trouble when asked to recall a short list of words (a standard test of memory). People in that study group also found it very hard to focus their attention on the tests given to them. As people age, they normally lose nerve cells in a region of the brain that is important for remembering events. Chronic exposure to THC may hasten the age-related loss of these nerve cells. In one study, researchers found that rats exposed to THC every 8 months (about 1/3 of their life span) showed a loss of brain cells comparable to rats that were twice their age. It is not known whether a similar effect occurs in human. Researchers are still learning about the many ways that marijuana could affect the brain. 

Q: Can the drug cause mental illness?
A: Scientists do not yet known whether the use of marijuana causes mental illness. Among the difficulties in this kind of research are determining whether drug use precedes or follows mental health problems; whether one causes the other; and/or whether both are due to factors such as genetics or environmental conditions. High doses of marijuana can induce psychosis (disturbed perceptions and thoughts), and marijuana use can worsen psychotic symptoms in people who have had schizophrenia. There is also evidence of increased rates of depression, anxiety, and suicidal thinking in chronic marijuana users. However, it is not yet clear whether marijuana is being used in an attempt to self-medicate an already present, but otherwise untreated, mental health problem or whether marijuana use leads to mental disorders (or both).


Q: Do marijuana users lose their motivation?
A: Some frequent, long-term marijuana users show signs of a lack of motivation (sometimes termed "amotivational syndrome"). Their problems include not caring about what happens in their lives, no desire to work regularly, fatigue, and a lack of concern about how they look. As a result of these symptoms, some users tend to perform poorly in school or at work. Scientist are still studying these problems.

Q: Can a person become addicted to marijuana?
A: Yes. Although not everyone who uses marijuana becomes addicted, when a user begins to seek out and take the drug compulsively, that person is said to be dependent on the drug or addicted to it. In 2004, more than 298,317 people entering drug treatment programs reported marijuana as their primary drug of abuse, showing they needed help to stop using. Some heavy users of marijuana show signs of withdrawal when they do not use the drug. They develop symptoms such as restlessness, loss of appetite, trouble sleeping, weight loss, and shaky hands. According to one study, marijuana use by teens who have prior serious antisocial problems can quickly lead to dependence on the drug. That study also found that, for troubled teens using tobacco, alcohol, and marijuana, progression from their first use of marijuana to regular use was about as rapid as their progression to regular tobacco use and more rapid than the progression to regular use of alcohol. 

Q: What is "tolerance" for marijuana?
A: "Tolerance" means that the user needs increasingly larger doses of the drug to get the same desired results that he or she previously got from smaller amounts. Some frequent, heavy users of marijuana may develop tolerance for it.

Q: Are there treatments to help marijuana users?
A: Up until a few years ago, it was hard to find treatment programs specifically for marijuana users. Treatments for marijuana dependence were much the same as therapies for other drug abuse problems. These include behavioral therapies,  multi systemic therapy, individual and group counseling, and regular attendance at meeting of support group, such as Narcotics Anonymous. Recently, researchers have been testing different ways to attract marijuana users to treatment and help them abstain from drug use. There are currently no medications for treating marijuana dependence. Treatment programs focus on counseling and group support systems. From these studies, drug treatment professionals are learning which characteristics of users are predictors of success in treatment and which approaches to treatment can be most helpful. Further progress set up to help adolescents in particular. Some of these programs are in university research centers, where most of the young patients report marijuana as their drug of choice. Others are in independent adolescent treatment facilities. Family physicians can be a good source for information and help in dealing with adolescents' marijuana problems.

Q: Can marijuana be used as medicine?
A: There has been much debate in the media about the possible medical use of marijuana. Under U.S> law since 1970, marijuana had been a Schedule I controlled substance. This means that he drug, at least in its smoked form, had no commonly accepted medical use. In considering possible medical uses of marijuana, it is important to distinguish between whole marijuana and pure THC or other specific chemicals derived from cannabis. Whole marijuana contains hundreds of chemicals, some of which may be harmful to health. THC, manufactured into a pill that is taken by mouth, not smoked, can be used for treating the nausea and vomiting that go along with certain caner treatments and is available by prescription. Another chemical related to THC (nabilonecannabinoids) may have other medical used. According to scientists, more research needs to be done on marijuana's side effects and potential benefits before it can be recommended for medical use. However, because of the adverse effects of smoking marijuana, research on other cannabinoids appears more promising for the development of new medications.

Q: How can I prevent my child from getting involved with marijuana?
A: There is no magic bullet for preventing teen drug use. But parents can be influential by talking to their children about the dangers of using marijuana and other drugs. and by remaining actively engaged in their children's lives. Even after teens enter high school, parents can stay involved in schoolwork, recreation, and social activities with their children's friends. Research shows that appropriate parental monitoring can reduce future drug use, even among those adolescents who may be prone to marijuana use, such as those who are rebellious, cannot control their emotions, and experience internal distress. To address the issue of drug abuse in your area, it is important to get involved in drug abuse prevention programs in your community or your child's school. Find out what prevention programs you and your children can participate in together.


Resources: National Clearinghouse for Alcohol and Drug Information: 1-800-729-6686. Visit NIDA's Web site at www.drugabuse.gov, www.marijuana-info.org, and www.teens.drugabuse.gov